Or you can fly into Naples and have a private car service take you to directly to your Amalfi coast

A note from Fodor s: As of February 1, 2013, Fodor's Travel, a division of Random House, has replaced our privacy policy with Random House's single policy. Please take a few minutes to read our updated Random House, Inc. Privacy Policy and Terms of Use .
Most US airlines only have non-stop flights from the US to either Rome or Milan. You could fly into Rome and train to Naples or Salerno (depends on your final destination on the coast) and travel the rest of the way by bus or ferry. Otherwise, you will need to do connecting flights to Naples and then train/bus/ferry.
In addition to the Air France option mentioned orlando hotel deal above, be aware that several U.S. airlines fly into Naples via connections on their alliance partners. For example, I booked my recent trip to Naples on United connecting through Munich, but the Munich to Naples leg was on Lufthansa. Delta partners with Air France, and I believe orlando hotel deal USAirways and/or American partner with Alitalia. It might put your mind at ease to research some of the options and pairings on the airline websites before booking on Travelocity or Expedia. The issue you may wish to research is what happens if, e.g., you booked the flights I took not through United but through Travelocity and you miss your connection. You'll want to be sure that the second airline will rebook you on a later flight. My guess is that would likely be the case for any of the alliance pairs mentioned orlando hotel deal above, but I don't know, better to get a (written) answer from the horses's mouth. Good luck!
Or you can fly into Naples and have a private car service take you to directly to your Amalfi coast destination -- not the absolute cheapest option, but not necessarily a bad deal either. And it is probably the best option if dealing with luggage and minimizing transfers is truly a concern.
All good thoughts! I understand many flight options but didn't want to spend so much time in airports..I can get to Rome easy enough but long delay before flight to Naples..and ultimately on to Positanio or Ischia
Well, not a great idea .... need to factor the time it'll take to get from point A to B, packing/unpacking, checking in/out hotel. Assume orlando hotel deal by your choice of destination, you are seeking R R ...... dashing from one city to next isn't best approach to relaxing getaway. At most, pick two; with one being Positano, and then select either Ischia or Capri.